Go to www.biology.arizona.edu - click on Karyotyping under human biology.
Fill the following worksheet.
Fill the following worksheet.
Introduction:
1. What causes a dark band on the chromosome? _____________________________________
2. What is a centromere? _______________________________________________________
2. What is a centromere? _______________________________________________________
Patient Histories:
Click on Patient Histories. You will be completing a karyotype for Patient A, B & C
Patient A (Click on the link to “Complete Patient A’s Karyotype” )
Match the chromosome to its homolog. After all the matches are complete you’ll analyze your patient. (Scroll down to view your completed karyotype).
3. What is patient A’s history (summarize) ____________________________________________
4. How many total chromosomes are in your karyotype – count them _________
4. How many total chromosomes are in your karyotype – count them _________
The last set of chromosomes is the sex chromosomes, if you have two large chromosomes, your patient is XX (female), one large and one small indicates and XY (male).
What sex chromosomes does your patient have? ________ Which chromosome set has an extra + _______
5. What diagnosis would you give this patient (what disease)? ____________
Patient B - click on the link to go to Patient B and repeat the above process.
6. What is Patient B’s history (summarize) ______________________________________________
7. How many total chromosomes are in your karyotype – count them _________
What sex chromosomes does your patient have ________
Which chromosome set has an extra + _______
8. Finish the notation for this patient’s karyotype : 47 X _____
9. What is the diagnosis? __________________________________
What sex chromosomes does your patient have ________
Which chromosome set has an extra + _______
8. Finish the notation for this patient’s karyotype : 47 X _____
9. What is the diagnosis? __________________________________
Patient C - click on the link to go to Patient C and repeat the above process.
10. What is patient C’s history (summarize)? _________________________________________
11. How many total chromosomes are in your karyotype – count them _________
What sex chromosomes does your patient have ________
Which chromosome set has an extra + _______
12. Write out the correct notation for this karyotype. ________
13. What is the diagnosis? _________________________________________
11. How many total chromosomes are in your karyotype – count them _________
What sex chromosomes does your patient have ________
Which chromosome set has an extra + _______
12. Write out the correct notation for this karyotype. ________
13. What is the diagnosis? _________________________________________
